Ozone Therapy and Lyme Carditis

The purpose of this study was to determine if oxygen/ozone therapy affected Lyme disease caused by the spirochete, Borrelia Burgdorferi.

The spirochete, Borrelia Burdorferi is a microaerophilic organism carried by the deer tick (Ixodid) and transferred to humans and other mammals by its bite. Symptoms often are a bulls eye rash and erythema migrans. Other symptoms may include pain in joints and muscles, sore throat, fever, swollen glands and mental fogginess. If not diagnosed within one month or two months, the disease may become a chronic infection. At that point of time it becomes sequestrated in fibroblasts and other cells which, in turn appear to protect it against the effective treatment by all known antibiotics so far tested. The disease is difficult to diagnose without serological findings and requires the skill of a highly qualified physician, experienced in treating this disease.

Lyme disease is caused by a tick-borne spirochete (Borrelia burgdorferi). It usually begins during the summer months with a characteristic rash (erythema chronicum migrans), followed in weeks to months by neurological, joint, or cardiac involvement.   Some clinical manifestation may persist for years.

   About 10 percent of patients with Lyme disease develop evidence of transient cardiac involvement, the most common manifestation being variable degrees of atrioventricular block at the level of the atrioventricular node. Syncope due to complete heart block is frequent with cardiac involvement because often there is an associated depression of ventricular escape rhythms. Ventricular tachycardia occurs uncommonly. Diffuse ST segment and T wave abnormalities and transient, usually asymptomic, left ventricular dysfunction may be found in some patients, although cardiomegaly or symptoms of congestive heart failure are rare. A positive gallium or indium antimyosin antibody scan may point to suspected cardiac involvement in this disease. The demonstration of spirochetes in myocardial biopsies of some patients with Lyme carditis suggests that the cardiac manifestations are due to a direct toxic effect, although there is speculation that immune-mediated mechanisms may be involved as well.

   The value of specific therapy in Lyme carditis remains uncertain, and even without therapy the disease usually is self-limited with complete recovery the rule. Nevertheless, it is thought that treating the early manifestations of the disease may prevent development of late complications. Patients with second-degree or complete heart block should be hospitalized and undergo continuous ECG monitoring. Temporary transvenous pacing may be required for up to a week or longer in patients with high-grade block. Although the efficacy of antibiotics is not established, they are utilized routinely in Lyme carditis. Intravenous antibiotics (ceftriaxone, 2 gm, or penicillin G, 20 million units daily for 14 days) are suggested, although oral antibiotics (doxycycline, 100 mg twice daily, or amoxicillin, 500 mg three times daily for 14 to 21 days) may be used when there  is only mild cardiac involvement (first-degree atrioventricular block of less than 40 milliseconds duration). Whether anti-inflammatory agents (salicylates, corticosteroids) can ameliorate heart block is not clear.

RELAPSING FEVER

Many infections are currently observed in Ethiopia. During pandemics, mortality may be particularly high, reaching 70 percent, although sporadic cases are often more benign. Cardiac involvement is said to be a common complication and is often implicated as a cause of death, although one report involving 63 children did not find evidence of cardiac involvement. Atrioventricular conduction defects occur frequently and may be responsible for sudden death, although tachyarrhythmia’s have also been implicated. Numerous petechiae are observed with a diffuse histiocytic interstitial inflitrate, particularly around small arterioles in the left ventricle.

SYPHILIS

Aortitis is the most common manifestation of luetic involvement of the cardiovascular system. Aortic regurgitation and coronary ostial narrowing are associated findings. Syphilitic involvement of the myocardium itself in the form of gumma formation is uncommon and usually unsuspected clinically . Involvement of the base of the interventricular septum may result in damage to the conduction system and atrioventicular block. In one case a ruptured left ventricular aneurysm was found as a result of syphilitic endarteritis.

FUNGAL INFECTIONS OF THE HEART

Cardiac fungal infections occur most frequently in patients with malignant disease and/or those receiving chemotherapy, corticosteroids, radiation, or immunosuppressive therapy. Cardiac surgery, intravenous drug abuse, and infection with HIV are also predisposing factors for fungal cardiac involvement; namely

  1. Actinomycosis
  2. Aspergillosis
  3. Blastomycosis
  4. Candidiasis
  5. Coccidiodomycosis
  6. Cryptococcosis
  7. Histoplasmosis
  8. Mucormycosis
  9. Acute Trypanosomiasis

CLINICAL MANIFESTATIONS

 

These include fever, muscle pains, sweating, hepatosplenomegaly, myocarditis with congestive heart failure, pericardial effusion, and, occasionally, meningoencephalitis. Most patients recover, and their symptoms resolve over several months. Young children most commonly develop clinical acute disease and generally are more seriously ill than adults.

My point is Recirculatory Haemoperfusion™ is the only treatment for the above, without any side effects. There are many patients in my research whose Lyme disease treatment resulted in complications due to JARISH-HERXHEIMER REACTION (JRH).”

For Example: Lyme patients who   WERE treated with amoxicillin became very ill after the first dose of antibiotics.  They were hypertensive, their temperature shot up, they experienced rigor, some were hypotensive and we started normal saline. This is a systemic illness. The JHR was first noted in association with antibiotic therapy for neurosyphlis. Thus, the administration of antibiotics may bring about JHR.

The patients who were on RHP™ had no JRH and their conditions resolved.  All Lyme symptoms and complications abated and clinical testing showed all signs of Lyme infestation were gone from their systems. AND THEIR CONDITIONS RESOLVED.